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Epigenetic mechanisms relating developmental stress, nutrition and/or environmental chemicals, to behaviour and neuroendocrine function have been implicated in both animal and human studies.
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Depression is characterized by blunted behavior and neuroendocrine function that generally improve with antidepressant treatment.
We investigated whether weaning, which involves maternal separation, at different ages, altered subsequent behaviour, physiology and neuroendocrine function in young pigs.
Adipokines have a range of essential physiological roles, including adipocyte differentiation, glucose and lipid metabolism, satiety, immune regulation, cardiovascular function, and neuroendocrine function [ 37].
The changes observed in behavioral patterns and responses to light may be the consequence of alcohol-induced disruption of normal tissue/organ function and neuroendocrine function.
Genetic association studies have highlighted a potential role in the etiopathogenesis of these disorders for several genes related to vascular, neuronal and neuroendocrine functions.
The inhibition of CAs, which regulate intracellular and extracellular pH, can severely abrogate homeostatic and neuroendocrine functions [ 16, 17].
Additionally, MCP-1 has been suggested to act as a modulator of neuronal activity and neuroendocrine functions [ 61, 62].
Regulation of brain and neuroendocrine functions utilizes profiles of neuropeptides that together function to mediate the complex cell cell communication network among organ systems.
Melatonin is a potent neuromodulator, and plays an important role in physiologic and neuroendocrine functions' regulation via the high-affinity MT1 and MT2 receptors [ 23, 29].
Neurotransmission and neuroendocrine functions were the focus because of relevance to neural excitability and previous midshipman studies focusing on these mechanisms.
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