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However, the impairment of social behaviors in this model is resistant to both clozapine and haloperidol treatment.
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Drugs used in the pharmacological treatment of ADHD, usually catecholamine agonists have been shown to reduce ADHD-like behavior in this model [ 19, 22- 25].
Provided that these impairments are, at least in part, relevant to negative symptoms, screening of novel compounds to normalize this behavior in this model may lead to the identification of new treatments for negative symptoms.
The sequence of events and features of the behaviors observed in this model simulated those observed in human TLE.
More studies in fully back‐crossed (generation 10+) animals are required to better determine if indeed autism‐relevant behaviors exist in this model.
These four are considered overarching behaviors in the model as they are not specific to any particular step.
Besides, the driver behavior used in this model is also close to real life.
The wide range of dynamical behavior seen in this model emphasizes the need to understand the impact of our model assumptions on the predicted dynamics.
These results demonstrate that DBV stimulation of the ST36 acupoint inhibits the formalin-induced activation of spinal astrocytes and nociceptive behaviors in this inflammatory pain model and this inhibition is associated with the activation of spinal alpha-2 adrenoceptors.
The soil-pile interaction was simulated by adopting tangential and normal contact behavior in the model.
These values were tuned to ensure bistable switching behavior in the model.
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