This paper provides an overview of the design and rationale for a trial investigating whether lorcaserin, when combined with behavioral weight loss maintenance sessions (WLM), will facilitate the maintenance of losses of ≥ 5% of initial weight.
In a randomized control trial comparing PLP (n = 72) with a 6-month standard behavioral weight loss maintenance program (n = 72), PLP participants were 5.1-fold more likely to maintain weight loss than the standard program participants for those who attended at least half of the sessions (38).
This protocol describes a randomized, controlled trial of a comprehensive behavioral weight loss and weight maintenance program among persons with serious mental illness that attend psychiatric rehabilitation day programs across Maryland.
During both phone and group contacts, the health counselor used a facilitator guide and covered behavioral principles important to weight loss maintenance such as relapse prevention, problem solving, stress management, enhancing motivation, and social support.
The group session format consisted of a check-in with review of progress component, discussion of a behavioral topic related to weight loss maintenance, nutrition and physical activity hands-on experience with discussion, and a goal-setting with action-planning segment at the end of the session.
To our knowledge, no studies have examined the behavioral factors associated with long-term weight loss maintenance in medically underserved rural populations of older adults.
"[But] ultimately, successful weight loss maintenance will require behavioral and environmental interventions".
It was hypothesized that behavioral weight loss program (BWLP) participants who received an additional MI would evidence superior weight loss maintenance compared to participants who received a BWLP alone (no contact [NC]).
Poor self-regulation, as measured with various questionnaires and behavioral measures, has also been shown to predict less weight loss, less weight loss maintenance or more attrition to weight loss programs [ 27, 28, 30, 40, 53].
The current study provides further evidence that behavioral intervention in combination with diet and exercise produces modest long term weight loss maintenance and improvements in physical and mental quality of life measures.
The second part (3 12 months) focused on weight loss maintenance through further intervention with physical exercise and cognitive behavioral training, see Figure 1.
