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Previous studies investigating the relative contribution of HCRT actions at HCRTr1 and/or HCRTr2 across physiological and behavioral processes have been limited largely to studies examining the influence of HCRT on sleep/wake activity.
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Although the basic components of behavioral safety processes have been studied and widely documented, the current safety literature reveals several gaps in knowledge.
Although stimulants are generally associated with enhanced information processing, reports of stimulant effects on behavioral functions that rely on inhibitory processes have been inconsistent.
At the behavioral level, increases in acuity for auditory and tactile processes have been reported.
Gray matter thinning is associated with synaptic pruning, myelination, and apoptosis, and these processes have been suggested to underpin cognitive and behavioral development.
We were interested in whether such processes have been coopted by males to potentially manipulate female physiological and behavioral responses for their own benefits.
Interest in behavioral monitoring and evaluative processes has been heightened by the discovery of an event-related potential (ERP) component referred to as the error-related negativity (ERN) [ 2] or error negativity (Ne) [ 3].
While valid and reliable preclinical assays for reward-related behaviors are critical to understanding addiction-related processes, and various behavioral procedures have been developed and characterized in rats and primates, there have been relatively few studies using operant-based addiction-relevant behavioral paradigms in the mouse.
The process of craving involves physical, emotional, cognitive, and behavioral characteristics that have been well documented in the literature [ 10].
In behavioral sciences, sheep have been used in isolated cases for the study of facial recognition, as their mental process of recognition is qualitatively similar to humans.
Neuroendocrine, immune, and behavioral processes (such as depression) have been linked to stress-related preterm birth.
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