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Figure 6: Nilotinib protects against MPTP-induced behavioral deficits.
6-OHDA lesioned monkeys showed a variety of behavioral deficits.
These findings may be functionally relevant to some behavioral deficits seen in this animal model.
Markowska, A.L., Mooney, M. & Sonntag, W.E. Insulin-like growth factor-1 ameliorates age-related behavioral deficits.
These results indicate that nilotinib has neuroprotective effects against MPTP-induced behavioral deficits.
An ideal therapy (1) limits acute secondary injury and (2) ameliorates chronic behavioral deficits.
Currently there are no effective treatments targeting residual anatomical and behavioral deficits resulting from stroke.
Nguyen, R. et al. Parvalbumin and GAD65 interneuron inhibition in the ventral hippocampus induces distinct behavioral deficits relevant to schizophrenia.
We demonstrated that PBM significantly attenuated behavioral deficits and infarct volume induced by PT stroke.
It remains unknown, however, how these alterations map onto quantifiable behavioral deficits in patients.
This approach yields a remarkable survival rate but fails to prevent neurological and behavioral deficits.
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CEO of Professional Science Editing for Scientists @ prosciediting.com