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However, the mechanisms that underlie the behavioral changes induced by these abused drugs have not yet been elucidated.
The present study was designed to investigate the mechanisms how antipsychotic drugs suppress the behavioral changes induced by psychoactive drugs in mice.
This study was designed to shed further light on the impact of putative serotonergic neuronal degeneration in OBX mice and to assess the effect of a widely used antidepressant on serotonergic related behavioral changes induced by OBX.
Studies with animal models showed that cellular, structural, and behavioral changes induced by environmental enrichment are related to increased levels of brain-derived neurotrophic factor (BDNF) in the brain.
Most life-threatening complications result from muscle coordination and, to a lesser extent, behavioral changes induced by declining cognitive function.
We therefore hypothesize that clozapine, but not haloperidol, will retain the behavioral changes induced by fear conditioning following ketamine administration.
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In this study, we designated starvation time 3 h at 17 °C, 2 h at 20 °C and 1 h at 23 °C, respectively, because it was reported that behavioral change induced by starvation sufficiently occurs after cultivation at 17 °C for 3 h or after cultivation at 25 °C for 1 h (Mohri et al. 2005).
It is believed that the behavioral and neuropathological changes induced by KA are initiated by the activation of KA receptors in the CA3 region of the hippocampus [10], followed by release of the endogenous excitatory amino acids, glutamate, and aspartate [11], with an activation of all types of glutamate receptors.
The results show that deprivation of odor cues released by Ehrlich tumor-bearing mice reversed the behavioral, neurochemical and immune changes induced by cohabitation.
Using a well characterized animal model of migraine [15 18] based on the quantification of behavioral (nocifensive) and neurochemical changes induced by systemic nitroglycerin (NTG) - a vasodilator known to induce migraine-like headache in migraineurs [19 21] - we have gathered evidence to suggest a derangement of the endocannabinoid function in migraine.
This number of genes probably underestimates the expression changes induced by sleep/wake behavioral state in the brain given the limited statistical power of some of the component studies.
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