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These results provide robust evidence that EEG-awakening has excellent predictive accuracy for behavioral awakening.
In the following study, we examined the predictive value of EEG-awakening for behavioral awakening in comatose patients.
We propose a new term of EEG-awakening and demonstrate that it is an excellent predictor for behavioral awakening from coma.
EEG-awakening incorporates both EEG-R and sleep spindles and is an excellent predictor for early behavioral awakening in comatose patients.
We found that the combination of EEG-R and sleep spindles, termed EEG-awakening, presented better predictive accuracy for behavioral awakening than if either was used individually.
Here we aimed to investigate the potentially prognostic value of electroencephalogram-reactivity (EEG-R) in combination with sleep spindles, termed EEG-awakening, for behavioral awakening in etiologically diverse comatose patients.
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Repeated exposure to a novel noise during Rapid Eye Movements (REM) or light non-REM (NREM) sleep leads to improvements in behavioral performance upon awakening.
Second, behavioral performance upon awakening and neurophysiological markers extracted during sleep revealed a sharp distinction between REM and light NREM sleep on the one hand and deep NREM sleep on the other: while REM and light NREM sleep induced learning, deep NREM sleep suppressed learning.
Sleep inertia (SI) denotes a period of hypovigilance, confusion and impaired cognitive and behavioral performance that immediately follows awakening.
We used onset of behavioral movement as a surrogate marker for onset of emergence, and this has been used with other behavioral measures such as crying (or attempting to cry), gagging on an endotracheal tube, eye opening and looking around to describe awakening in neonates and infants (Bould et al., 2011 Pediatric Anesthesia).
It was an awakening.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com