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Decreasing the matrix shear modulus increases the anisotropic nature of the mechanical behavior of the leaflet and causes a more pronounced biaxial loading condition.
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The cable elements are part of the discrete fiber model we developed [18] to model the highly nonlinear, anisotropic material behavior of the leaflets in a computationally efficient manner.
In this study, TAV and SAV leaflet fatigue due to cyclic loading was investigated through finite element analysis by implementing a computational soft tissue fatigue damage model to describe the behavior of the pericardial leaflets.
Especially, SFG was used to examine the behavior of each leaflet of the lipid bilayer while interacting with micron/nanoparticles. Experiments of SFG show direct evidences that micron/nanoparticles attachment lead to the lipid orientation.
We used bovine veins to study the behavior of valve leaflet tissue and adjoining wall tissue (from the proximal and distal ends of the veins) under different biaxial testing protocols.
Biaxial stress-stretch behavior of the mitral valve anterior leaflet at physiologic strain rates.
This novel result further suggests that while the MVICs may be phenotypically and biomechanically similar throughout the leaflet, they experience layer-specific mechanical stimulatory inputs due to distinct extracellular matrix architecture and mechanical behaviors of the four MV leaflet tissue layers.
Valvular aneurysm Loss of the homogenous curvature of the leaflet Valvular thickening Leaflet thickened Difficult to assess when lesions are degenerative or calcified.
In the following, we present the full text of the leaflet.
Flexure is a major deformation mode of the aortic valve (AV) leaflet, particularly in the commissural region where the upper portion of the leaflet joins the aortic root.
This leaflet is an updated version of the leaflet used in the second round.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com