Sentence examples for behavior of malignant MECs from inspiring English sources

Previous studies showed that IL-4 could enhance the invasive behavior of malignant MECs (mammary epithelial cells) and promote their dissemination and outgrowth in the lung through regulating the polarization of M2 macrophages.

LRP-1 thus appeared as an attractive receptor for targeting the invasive behavior of malignant cells.

The infiltrative behavior of malignant glioma cells is a function of two phenotypes, migration and invasiveness.

These results raised a potential that the behavior of malignant glioma cells may be similarly reprogrammed.

Knowledge about malignant tumors allows us to better understand the behavior of malignant cells and to unveil the mechanisms that initiate tumorigenesis.

Histology revealed extensive infiltration and resorption of the adjoining bone as signs for typical growth behavior of malignant tumors.

Intracerebral injection of GSCs into immunodeficient mice generates highly infiltrative tumor xenografts that closely mimic the behavior of malignant gliomas.

Thus, it is important to identify genetic alterations that affect the behaviors of malignant tumors.

Moreover, they suggest that targeting FAK and other constituents of the focal adhesion complex, such as integrins, p130Cas, talin, or paxillin, holds the potential to inactivate specifically the oncogenic activities of TGF-β in malignant MECs.

Recently, Sox4 was identified as a TGF-β gene target in normal and malignant MECs undergoing EMT and as a potential biomarker of triple-negative breast cancers (TNBCs) [ 12, 13].

The results appear to suggest a correlation between the down-regulation of LEA.92 and the development of tumorigenicity in malignant MEC lines.