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Moreover, a characteristic behavior of expression of prohibitin which may have multiple functions including mitochondrial chaperone activity (Tatsuta et al. 2005; Van Aken et al. 2009) was up-regulated in oCG 2010, while it was down-regulated under oCG 2009.
Even if metabolic regulation of highly correlated genes is shown not to occur or is minimal, observing the behavior of expression within a broader physiological and biochemical context through a network correlation analysis may reveal as of yet unknown interactions.
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Gene symbols were colored according to the temporal behavior of their expression (red indicating up- and green down-regulated expression).
Because the regulation of gene expression is a dynamic process, the expression profiling was presented over a time course by cDNA-AFLP, which allowed us to study the dynamic behavior of gene expression and characterize their changes over time.
Using this data set, we analyzed the behavior of protein expression levels as a function of codon bias and found that increasing AA bias correlates with an increasing likelihood that a protein will exhibit decreased expression (fold change ≤ − 2) (Fig. 3b and Supplementary Data 2).
This conceptualization and operationalization of emotional labor departs from existing efforts because it focuses on the behavior of emotional expression, encompassing genuine, faked, and suppressed positive and negative emotional displays.
Furthermore the different position of maspin inside the cell or its epigenetic modifications may explain the different behavior of the expression of maspin between tumors.
The core response module appears to be highly relevant to macrophage activation as we showed by training on TLR agonist and Salmonella infection and very accurately predicting the dynamic behavior of gene expression under nanoparticle exposure.
Here we use these statistics to examine the behavior of differential expression with transcript length.
The treatment interfered with the behavior of mRNA expression for TGF-β1 versus the other factors considered.
Additionally, many methods are now focusing on using time-course behavior of gene expression along with available biological knowledge.
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