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Biomaterials designed to mimic the intricate native extracellular matrix (ECM) can use a variety of techniques to control the behavior of encapsulated cells.
These results indicate that signal RGD peptide clustering is an additional hydrogel design parameter can be used to influence and guide the behavior of encapsulated cells.
This opacity obstructs light-based observation of the morphology and behavior of encapsulated cells.
This low light transmittance obstructs the observation and in-depth investigation of the morphology and behavior of encapsulated cells.
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The microenvironmental factors within microcapsules play an important role in influencing the behaviors of encapsulated cells.
Furthermore, we clarified the effect of microenvironmental factors on the behaviors of encapsulated cells and the methods about improving the microenvironment of microcapsules.
The generated biochemical photopatterns of this sequential click approach were not only well-defined, but more importantly displayed remarkable impact on dynamic cellular behaviors of encapsulated cells.
Gal-3 promoted a dose-dependent delay in the growth of encapsulated cells of C. neoformans (Fig. 6a).
This structural advantage improved viability and functions of encapsulated cells and permitted micron-scale structures to control over spatial distribution of incorporated cells.
Improved strategies are needed, however, to optimally balance hydrogel permeability to support metabolic activities of encapsulated cells, while maintaining patternability to restore key aspects of tissue architecture.
However, the presence of the reactive aldehyde groups can compromise the viability of encapsulated cells.
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