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Rapid progress in developing organ-on-a-chip platforms has aroused interest in building pharmacokinetics-pharmacodynamics (PK-PD) models to study drug behavior in multiorgan systems.
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OBJECTIVE: Neonatal and infant cardiopulmonary bypass results in multiorgan system dysfunction.
If not recognized and treated in timely manner, ACS can result in multiorgan system failure and death.
In vitro microphysiological multiorgan systems using human cells provide a novel method to identify promising drug candidates and eliminate potentially toxic compounds from clinical trials.
The result further confirmed the bifurcation behavior in neuronal systems.
Frailty is a common and important geriatric syndrome characterized by age-associated declines in physiologic reserve and function across multiorgan systems, leading to increased vulnerability for adverse health outcomes.
It affects multiorgan systems including reproduction.
In the future, by means of improvements in tissue engineering industry, it is foreseen to establish their organ banks from the healthy citizens and to test the effects of drugs on tissues and multiorgan systems, which end up with the personalized medicine.
Hamiltonian chaos, then, is chaotic behavior in a Hamiltonian system.
Hepa Wash was a safe procedure and improved multiorgan system failure in pigs with ALF.
Surgical repair was performed in only 1 patient and declined in the remaining because of comorbidities and multiorgan system failure.
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CEO of Professional Science Editing for Scientists @ prosciediting.com