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Both mouse and human iPSCs are similar to embryonic stem cells (ESCs) with respect to their morphology, cell behavior, gene expression, epigenetic status and differentiation potential both in culture and in vivo.
the URX, AQR, and PQR O2-sensing neurons are tonically stimulated by 21% O2, causing sustained changes in C. elegans behavior, gene expression, and circuit state.
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Animal models that examine the effects of natural genetic variation, the effects of mutations, and the effects of targeted genetic engineering on behavior have been instrumental in understanding the influence of genes on behavior and the influence of behavior on gene expression.
Numerous studies have demonstrated that its genetically encoded period length (the time taken for one complete cycle under constant conditions) directly affects the phase of human behavior and gene expression: individuals with longer periods have a later phase than those with shorter periods, looking either at human behavior or at gene expression [ 7- 9].
Neurons have a large diversity of shapes, electrical behavior, and gene expression signatures that together determine the role of each neuron in the brain.
Advances in synthetic biology have enabled the engineering of cells with genetic circuits in order to program cells with new biological behavior, dynamic gene expression, and logic control.
These stable variations in maternal behavior influence gene expression and stress responses in the offspring [18] [20].
Changes in behavior and gene expression under constant darkness were also monitored under laboratory conditions.
A significant impact of recent experience may also apply to other levels of organization, from brain and behavior to gene expression, but is often neglected in experimental protocols.
The core response module appears to be highly relevant to macrophage activation as we showed by training on TLR agonist and Salmonella infection and very accurately predicting the dynamic behavior of gene expression under nanoparticle exposure.
How tumor cells respond to matrix rigidity is an area of increasing interest, with several groups investigating how the increasing rigidity of soft tissue can alter tumor cell behavior and gene expression.
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