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Analyses of ground-based experiments on near-critical fluids to precisely determine their density can be hampered by several effects, especially the density stratification of the sample, the liquid wetting behavior at the cell walls, and a possible singular curvature of the "rectilinear" diameter of the density coexisting curve.
Finally, the effect of intrinsic noise at the cell population level was found to be markedly different than at the single-cell level, emphasizing the importance of simulating entire cell populations and not just individual cells to understand the complex interplay between single-cell genetic architecture and behavior at the cell population level.
Primary cells derived from Fmn1-IV knock-out mice demonstrated altered processive behavior at the cell periphery coupled with a delay in cell spreading and altered focal adhesion formation.
Thus, our results do not explicitly contradict those of Mizuno et al.; it is plausible that reconstituted actin networks better mimic actin behavior at the cell cortex where motor activity is a dominant factor, whereas in vivo microrheology probes the cytoplasmic actin network decoupled from stress fibers.
In addition, elongated cell shape, parallel microtubule organization, and microtubule behavior at the cell cortex was restored (see above; Figure 3, Table 1).
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In this experimental setup, which mimics the situation in the root canal, the pretreatment of dentin might influence cellular behavior at the cell-dentin interface.
Cell-to-cell variability can lead to different qualitative behavior at the single cell level but also in cell populations, in particular in systems showing bistability (all-or-nothing effects) or oscillatory behavior [ 26, 27].
This statistical perspective is made cogent by the recognized fact that a largely stochastic and unpredictable behavior at the single cell level is paralleled by very strongly repeatable phenomena observed when a large population of cell is taken into consideration.
Matrix-bound VEGF, however, has a biphasic behavior; at the tip cell, isoforms with intermediate and lower affinity to HSPGs satisfy the requirement that MMP effects oppose HSPG binding effects, but above an affinity limit this is violated.
Surprisingly and counterintuitively, bimodality does not require switch-like behavior at the single-cell level, but can arise from cell-to-cell variability in protein expression and a pathway activation threshold.
This hybrid structure may potentially enable induced 'auxetic' behavior at the single-cell scale while tuning the Poisson's Ratio to a more isolated value.
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behavior at the level
behavior at the destination
behavior at the top
behavior at the end
behavior at the world
behavior at the hospital
behavior at the range
behavior at the hearing
behavior at the police
behavior at the party
behavior at the drinking
behavior at the university
behavior at the household
behavior at the feed
behavior at the grade-school
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