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The essential parameters for Linus that December were bond angles and length, not what DNA did biologically or how it behaved in solution.
Unfortunately, this mutant was poorly behaved in solution and was not amenable to biophysical measurements.
As many PRDs are well behaved in solution, they are ideal model systems for studying protein-protein interactions and ligand binding specificity.
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AGP would behave in solution as a branched or hyper-branched polymer with conformations ranging from globular to elongated shape depending on the size of the carbohydrate branches.
This observation, together with the value of the Mark-Houwink-Sakurada exponent, a<1, indicates that these polymers do not behave in solution as rigid-rod polymers, but most likely as worm-like chains with a relatively large persistence length.
Recombinant latherin (rlatherin) was produced without its hydrophobic secretory signal peptide and purified in high yield by over-expression in E. coli, and found to behave in solution as a well-folded globular protein, yet with significant surfactant properties, as follows.
18a, 19a Two of the most easily manipulable factors that influence how DNA behaves in solution are temperature and salt concentration.
The effective size of the protein in DPC micelles was assessed by SEC-MALS and TRACT [27] experiments, which indicated that S1R Δ35) behaves in solution as a ∼29kDa complex.
While soils supplied with NaCl solution behaved in a similar fashion during their first freeze-thaw cycle, the second cycle saw a reduction in the rate of migration of the freezing front within the soils and also less ice segregation and less heave due to increased salinity.
If the objective function is well behaved, in the sense that good solutions tend to contain good partial solutions, it will explore all attractive regions of the solution space and while it may miss the global optimum owing to the increasing coarseness of the search, it will not miss an entire good region.
It means that the mechanically polished Mo-electrode behaves in aqueous solutions at constant oxygen concentration like a pH-indicator electrode.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com