Sentence examples for behaved as a partial from inspiring English sources

In multiple in vitro assays, aripiprazole behaved as a partial agonist at 5-HT1ARs [ 55].

Despite these in vitro assays, where aripiprazole behaved as a partial agonist, the compound exerted full agonistic properties in an electrophysiological study.

In C6-glioma cells expressing low levels of endogenous 5-HT1ARs, arinducedole induced phosphatidyl-inositol (PI) hydrolysis only at the highest concentrations and significantly less than did serotonin, while in 5-HT1AR-transfected GF62 cells, expressing high levels of the receptors, aripiprazole still behaved as a partial agonist but with a slightly higher intrinsic activity [ 36].

Methoxymethylenoxy derivative 9 showed the best 5-HT1A selectivity profile and the highest potency at 5-HT1A receptor, behaving as a partial agonist.

The analog in which glycine was substituted for histidine at position 2, [Gly2]LRF, behaves as a partial agonist releasing less than 50percentt of the luteinizing hormone secreted at maximum concentrations of the releasing factor, while the analog in which histidine at position 2 is deleted has no significant agonist activity at any of the doses tested.

In addition, analysis at the clonal level demonstrated that hLFAαL (aa326-345) behases as a partial agonist for OspA-reactive T cells, not as a full agonist [ 13].

Moreover, Camp et al. [ 47] reported that troglitazone, but not rosiglitazone, may behave as a partial agonist under certain physiological circumstances and as a full agonist in others.

This molecule displays an excellent selectivity profile (>500-fold in binding assays) versus members of the steroid receptor family and behaves as a partial AR agonist in cell-based assays [ 26].

Formyl-NleWEDWVGWI behaved as a weak partial agonist with FPR W190/N192 but a stronger partial agonist with FPR R190/K192 and FPR R190/N192.

In addition, at the tβ3C-receptor, CGP12177 behaved as a typical partial agonist, inhibiting cimaterol at similar concentrations that cause a stimulatory effect, just as would be expected when both ligands (CGP 12177 and cimaterol) are competing at one single site (Figure 9b).

Particularly, compound 6a behaved as an MT1 partial agonist and MT2 full agonist and exhibited an excellent binding affinity at MT2 (Ki = 0.09 nM).