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If we do move full speed ahead on germline editing, what has begun as one targeted swipe at an autism-related variant could expand into a total blitz against any neurobiological condition that falls outside of some norm.
(Heidi Fleiss had begun as one of his 'Bernie's girls'.) 'Hefner didn't expect it.
For Regina Calcaterra, childhood might have begun as one etched in sand, but expect her to carry a legacy etched in stone.
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These spaces may have begun as ones for experimentation with drugs and with sexual practices, but they became the sites of alternative modes of cultural production.
A group of markets that began as one store on the Upper West Side plans to take over the Greenwich Village storefront recently vacated by another venerable market, Balducci's.
He began, as one did in those days, on a local paper – the Southport Visiter.
No, the Milky Way's disk is not a sphere, but it probably began as one.
The Dunbar Apartments began as one of America's grandest experiments in housing reform.
The debate began as one by one the seven candidates were called to the podium.
Paisley began as one of the most volatile elements in Northern Ireland's tempestuous political firmament.
That's in part because it began as one thing and then changed over time.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com