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Several case studies illustrate the interest of the approach, which can be used at the beginning of the optimization when sampling randomly in the design space.
At the beginning of the optimization process, the system generates a random seed fuel lattice, which is used to generate a set with 100 fuel lattices.
Increasing PAR reduce the HSA sensitivity to this parameter and lead to fast rise of reliability in the beginning of the optimization and high reliability at the end of the search.
The SPSA and NEWUOA methods achieved similar values, but the computational efficiency of NEWUOA was much lower at the beginning of the optimization process.
The testing procedure is an important player in determining the end of the training process and the beginning of the optimization process.
This variable is given by the user at the beginning of the optimization process, but it is changed by each specie agent according to the attained fitness value.
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At the beginning of the trial, the optimization based on Xrs resulted in a significantly higher PEEP compared with that set in the ARDSNet group.
Conversely, throughout design optimization iterations, the original period of a unit cell that is initially set at the beginning of design optimization can be maintained if branch overlapping is forced not to occur.
Long time-horizons are explored, aiming to avoid typical peaks in drug prescriptions found at the beginning and at the end of the optimization periods.
Considering the key polymer properties from the beginning of optimization process resulted in similar values in terms of NPV when compared with strategies that considered ideal polymer in the selection of project variables.
This begins in the optimization phase of the assay: In test runs with a small number of compound plates, the assay has to possess a sufficient signal window (e.g., Z-factor [ 15]), stability, and sensitivity (e.g., measured by the effects of known control compounds) [ 16, 17].
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