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But before all that happened--more than two decades before the civil rights legislation of the sixties and more than ten years before the Supreme Court's 1954 decision--a quiet drama was beginning in a small office in Brooklyn, New York, a drama that one observer later would call "perhaps the most visible single desegregation action ever taken".
In the beginning, in a small trial three patients suffering from ulcerative colitis were treated with ova from the pig whipworm Trichuris suis [ 43].
Many researchers may eschew this comparison but we believe that, right from the beginning in a small animal model, a novel approach must demonstrate at least equal effectiveness as compared to the clinical gold standard.
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What began in a small field in New Hampshire grew into a national movement.
The case began, in a small way, with The New Yorker.
The hearing began in a small room in the Dirksen Office Building.
The piece begins in a small, darkened room where audience members are guided to pillows on a carpeted floor.
Take the San Francisco Salsa Rueda Festival, a Cuban salsa event that began in a small San Francisco restaurant four years ago.
We began in a small bookshop in Brixton, and much of the collection was amassed by volunteers and individual donations.
Spraying for Dutch elm disease began in a small way on the university campus that very year.
As the last of the Pranksters was being cast in late April, taping had begun in a small studio near Lincoln Center in Manhattan on short segments.
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