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Most (if not all) PRV genes begin to be expressed from the onset of viral expression.
During regeneration, eye progenitors express conserved TFs ovo, six-1/2 and eya at a distance from the eye primordium, forming a trail of cells and undergoing changes in gene expression as they migrate toward the primordium, where differentiation markers begin to be expressed (Lapan and Reddien, 2011; Lapan and Reddien, 2012).
Concomitantly, genes important in starch accumulation begin to be expressed at 5 DAF with the onset of starch accumulation.
Markers that normally begin to be expressed after germ cells reach the gonad, such as Vasa, SYCP3, and SYCP1, showed reduced expression in Dazl−/−mutants of both sexes.
Our model incorporates processes that are carried out by phage genes that begin to be expressed at different times following infection [20].
Although the function of CD34, CD150, or c-Mpl is not essential for the development of HSCs [12], [35], [36], it is suggested that these HSC markers begin to be expressed at the embryonic HSC stage.
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Figure 4 figure supplement 2: It would be helpful to show here a stage series, showing when the BMP reporter normally begins to be expressed in the eye, and how levels of expression compare with other areas of BMP activity in the embryo.
Concomitant with Prox1 expression, the mature pan-neural marker NeuN begins to be expressed at 1 week after transplantation and levels increased up to 4 weeks following transplantation (Figure 6F, H).
Interestingly, however, the expression of phosphacan is initially downregulated and then begins to be expressed, with peak levels found approximately eight weeks after injury [ 8].
Our expression data provides evidence that in NLL, the conglutins began to be expressed at relatively high levels from 9-12 Dand and peaked between 33-38 DAA, which corresponds to the seed filling stage [ 28].
The transgene began to be expressed again in the resulting litters.
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