Pickwick began as high-spirited farce and contained many conventional comic butts and traditional jokes; like other early works, it was manifestly indebted to the contemporary theatre, the 18th-century English novelists, and a few foreign classics, notably Don Quixote.
We acknowledge that these maps also began as higher resolution sources, and thus errors of topography may be offset by improvements from resolution.
We are beginning, as high school valedictorians always promise, to make a difference.
The Great Leap would begin as high as a helium balloon could go: a hundred and thirty thousand feet — a quarter again as high as Kittinger went.
[19] In this approach, randomized trials begin as high quality evidence but can be rated down for apparent risk of bias, imprecision, inconsistency, indirectness, or suspicion of publication bias.
Using this approach, randomised trials begin as high quality evidence but may be rated down by one or more of four categories of limitations.
In the GRADE system of rating quality of evidence for each outcome, 20 24 randomised trials begin as high quality evidence but may be rated down by one or more of five categories of limitations.
Randomised trials begin as high-quality evidence, observational studies as low-quality evidence and case series and case reports as very low-quality evidence.
21 In the GRADE system of rating quality of evidence for each outcome, randomised trials begin as high-quality evidence, but may be rated down by one or more of five categories of limitations.
In this approach, RCTs begin as high-quality evidence, but may be rated down due to limitations related to risk of bias, indirectness, inconsistency (ie, heterogeneity), imprecision and publication bias.
In the GRADE approach, randomised trials begin as high-quality evidence but may be rated down by one or more of five categories of limitations: risk of bias, inconsistency, indirectness, imprecision and reporting bias.
