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The few studies that have examined this question so far have lead to rather conflicting results and beg the need for further experiments.
The correlations between PIK3CA mutations, good patient outcome, and low PI3K pathway activation (measured by gene expression profiling and IHC) beg the need for alternative methods indicative of PI3K pathway activation to identify ER+ tumors at risk of recurrence.
Similar(58)
A kingdom shrinks into the staccato to-and-fro of victor and vanquished: "I have no need to beg," the desperate Richard says.
The primal need to beg, the despair when your pleas are rebuffed or ignored.
While it would be nice to presume that large banks are chastened by their recent need to beg the public for capital, it is clear that financial services executives "just don't get it".
Historically speaking, this clause corrected one of the great weaknesses of the Articles of Confederation (the precursor to the Constitution), which had forced Congress to essentially beg the states for the revenues needed to run its business.
This unique dynamic begs the need for systemic thinking, with implications for program planning and delivery as a means of accompaniment.
The trends are of interest but, because of the limitations in the methodology discussed above, the lack of significance in some instances begs the need for additional studies using defined and more sensitive outcome measures.
Which begs the question, do brands need to pander to unconscious bias or use stereotypically gendered elements to positively move the needle in environmental impact?
So the new TV commercial begs the question: Do we need gay-only travel advertising?
Which begs the question: Do we need to be young and hot to have good sex?
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com