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Improvements in WES technology are needed before widespread clinical application.
However, key methodological factors must be addressed before widespread clinical application.
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There are few limitations to the technique that must be resolved before increased widespread clinical application of diffusion MR imaging of the chest.
Nonetheless, in view of the limitations of our study and especially the low number of patients with certain GHD, these results should be validated at other centers, as other decision rules in pediatric endocrinology have been [ 21], before any widespread clinical application.
From a clinical perspective the current study is of importance, since a new diagnostic test will not gain widespread clinical application before its acceptance by patients has been proven.
The simplicity and accessibility of this method should allow its widespread clinical application.
Widespread clinical application is hindered by toxicities related to recipient pre-conditioning.
Bone lengthening through callus distraction (callotasis) has widespread clinical application in the management of many orthopedic conditions [1, 2, 3, 4, 5, 6, 7].
This high cost leads to a restriction in widespread clinical application in areas such as surgical training or other repetitive processes.
Although a number of approaches are under investigation, none has been sufficiently successful to warrant widespread clinical application.
Although successful in selective treatments, tissue engineering needs to overcome major challenges to allow widespread clinical application with predictable outcomes.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com