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Monitoring before the third dose will thus be when the drug is being discontinued.
Vancomycin serum samples were drawn just before the third dose and 1 hour after administration of the third dose.
If levels are not measured until before the third dose many neonates on 24 or 36 hourly dosing regimens will have stopped the antibiotic before this level is due.
At 50 mg/kg, plasma Aβ1 42 levels were depleted to below the limit of accurate quantification within 1 h of administration and remained below the limit throughout the first dosing interval of 4 days in all animals and immediately before the third dose (Day 7).
The remaining patients formed the sparse sampling group, from whom one sample was taken in each of at least two of the following four time intervals: 0 to 1 hour (after the first dose but before the second dose); 1 to 3 hours (after the second dose but before the third dose); 3 to 8 hours (after the third dose); and 8 to 12 hours.
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Vitamin B12 injections (1000 μg intramuscularly) should also be started one week before the first dose of chemotherapy.
Infection consisted of the administration of two doses of 10 000 infective larvae of one of the nematode species, separated by an anthelmintic treatment and an interval of 1 week before the second dose was administered.
Before the second dose could be administered this patient developed ventricular fibrillation.
For vancomycin, trough serum concentrations should be obtained just before the fourth dose.
Patients received irinotecan at 40 mg/m(2) daily for 3 days, beginning just before the first dose of gemcitabine.
Each 8-week cycle included paclitaxel 90 mg/m2 provided intravenously weekly for 6 weeks, followed by 2 weeks off therapy and oral estramustine 280 mg twice daily for 3 days beginning 24 hours before the first dose of paclitaxel.
More suggestions(18)
before the third shot
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before the obatoclax dose
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