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Dendreon had always planned to have the independent data safety monitoring board (DSMB) for the trial take a look at the data before the study ended.
Patients were considered to have an interruption in care if they: (i) did not attend scheduled clinic visits for ≥3 months; (ii) did not return to care before the study ended on February 1, 2008; (iii) were not known to be in care at any other hospital or clinic during the study period; and (iv) were not known to have died [12], [14].
No data were analysed before the study ended.
In two of the six provinces infant immunization programs began 3 and 16 months, respectively, before the study ended.
We considered individuals who died from other causes before the study ended in 1996, or who remained alive as of 31 December 1996, as censored (competing-risks approach).
Patients were excluded if they intended on transferring out of the clinic catchment area before the study ended and/or if they were scheduled to start ART.
Similar(48)
The study ended before the projected sample size was obtained, which might have prevented effect detection in some outcome measures.
Assuming 40% drop out rate before the study ends, around 213 eligible subjects would have to be approached.
Critics say the studies ended before the true benefits or costs could be realized, that the checks were too small to produce clear results, that the people involved weren't a representative sample, or that the findings were misanalyzed.
Soft tissue sarcomas were included if they were diagnosed before the study end point of 31 December 1990, after which the completeness of ascertainment is uncertain.
Loss to follow-up from the clinic's ART program was defined as having missed ≥3 consecutive monthly refills before the study end date.
More suggestions(17)
before the trial ended
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before the study began
before the period ended
before the fight ended
before the day ended
before the inning ended
before the bell ended
before the season ended
before the ceremony ended
before the debate ended
before the quarter ended
before the war ended
before the year ended
before the session ended
before the presentation ended
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