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To solve this, some "leading zeros" are sent before the starting bit.
Some people are a long way down the track before the starting gun is fired.
Waiting at a track before the starting gun, we hear "saddles creaking like winches".
It was being called a classic game before the starting lineups were introduced.
Even before the starting gates open at Churchill Downs, Mr. Wolff will have an advantage over many other horseplayers.
But before the starting gate has even closed, riders are more intently focused on what will follow it.
To prevent that from happening, we inserted 6 bp (gccacc) in the sgRNA sequence right before the starting codon.
But those votes came before the starting wing player Monique Currie sustained a season-ending injury to her left knee five seconds into the first exhibition game.
Measuring these parameters accurately enough might even make the race itself redundant, allowing the winner to be anointed in the lab before the starting gun fires.
Seconds before the starting horn sounded, Mitch bailed out, perhaps put off by the fact that the pond was a gross green.
It will have the dramatic preparation, the anticipation before the starting gun, the confidence and the test of will, and finally the glory and pride as you make your final footsteps along Boylston Street.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com