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The second hypothesis is that the functional divergence of CAD genes occurred before the split of Class II and Class III from Class I. Further functional analysis of genes from Class I and Class II will be needed to answer this question.
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The first hypothesis is that CAD genes evolved defense function after the split of Class II and Class III from Class I genes.
Those of the fourth class evolved before the split of S. cerevisiae and other fungi (fungi class: node Fungi, node Dikarya, node Ascomycota, node Saccharomyceta, node Saccharomycetales and node Saccharomycetaceae).
Those with age 3 emerged before the split of fungi and other fungi/metazoa (fungi/metazoa class: node Fungi/Metazoa group).
Two fission events occurred after the split of Fragaria and before the split of Malus and Prunus.
The locus was very likely formed before the split of Hominoidea.
The original copy, Slc17a5B, was lost before the split of bony fish.
Earliness may also have been selected before the split of P. s. ssp.
Signals of positive selection in the LCA branch reflect either adaptation before the split of the two seagrass lineages or parallel evolution after their split.
The main adjustment was the split of the "Host Associated" class into obligate bacteria and facultative bacteria.
In the Rosoideae, TNL gene diversification occurred before and after the split of Rosa and Fragaria.
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