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The data before the normalization were shown in Table 1.
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The normalization was detectable well before clinical symptoms overtly improved.
The mean SERS spectra of different samples before the spectral normalization were shown in the Fig. 2.
Treatment may be difficult because administered base is often excreted before the desired normalization is achieved.
As before, digital normalization was applied to 50× using Jellyfish.
The maximum k cat values before normalization were 6.7, 3.5, and 1.04 s−1 for experiments using 0, 400, and 800 μM CTP, respectively.
The CTP synthesis vo values before normalization were 1.24, 18.5, and 0.82 μM/s for 200 nM CtpS, 4 μM CtpS, and 200 nM CtpSE277R, respectively.
The average difference between ES for scans reconstructed with STANDARD and BONE kernels before normalization were 7.2 ± 3.8 (range -3.0, 17.2) and -0.1 ± 0.5 (range -3.7, 0.9) after normalization.
The data were normalized together using a single round of the LOESS normalization algorithm within JMP Genomics, and distribution analyses conducted before and after normalization were used as a quality control step.
Statistical comparisons between original data before normalization were performed using Student's t-test and analysis of variance, where appropriate, with a p<0.05 considered significant.
After combining sets, mRNA (ORF) transcripts with fewer than 100 reads before normalization were excluded.
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