Exact(4)
Subject recruitment and allocation are summarized in Figure 3, the CONSORT flow diagram., All subjects gave written informed consent before the initiation of study protocols.
Previous neoadjuvant treatment for non-metastatic disease was allowed if completed at least 6 months before the initiation of study treatment.
Anovulatory patients will have a withdrawal bleed induced with a course of oral medroxyprogesterone acetate before the initiation of study medication.
One proposal that was made is that these be performed during a clinical trial's run-in phase, just before the initiation of study drug treatment as well as one month earlier.
Similar(56)
However, copeptin and IGFBP-1 were intentionally sampled soon after hospital admission, i.e., before the initiation of study-related or other treatments that could have influenced the biomarkers.
Ethical approval was obtained from the research ethics committee of the study center before the initiation of the study (MEC-2015-175).
Written informed consent was obtained from each study participant before the initiation of the study.
In the study, the study providers went through a 10-day, high-quality standard abortion training before the initiation of the study.
In this institutional review board-approved study, all participating sites provided necessary institutional data-sharing agreements before the initiation of the study.
A pilot study, including ten herds, randomly selected from the country's national registry, was conducted before the initiation of the study, to obtain prior information for estimation of the required sample sizes.
In addition, adjusted multivariate analysis, and the protocolization of initial resuscitation and management for severe sepsis and septic shock before the initiation of this study served to minimize the potential for selection bias.
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