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Vitamin B12 injections (1000 μg intramuscularly) should also be started one week before the first dose of chemotherapy.
Patients received irinotecan at 40 mg/m(2) daily for 3 days, beginning just before the first dose of gemcitabine.
Each 8-week cycle included paclitaxel 90 mg/m2 provided intravenously weekly for 6 weeks, followed by 2 weeks off therapy and oral estramustine 280 mg twice daily for 3 days beginning 24 hours before the first dose of paclitaxel.
All were pre-treated with bisphosphonate liposomes (100 ìl/mouse, obtained from Dr Nico van Rouijen) 24 h before the first dose of virus.
Electrocardiograms (ECGs) were obtained before the first dose and at the end of therapy.
Baseline blood samples were obtained before the first dose of dexamethasone.
Baseline was defined as the last recorded value before the first dose.
Erlotinib was taken orally, beginning 7 days before the first dose of chemotherapy.
Anti-meningococcal vaccination was administered before the first dose of eculizumab.
One occurred before the first dose and was not a treatment emergent adverse event (TEAE).
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The cutoff of 6 weeks was used to ensure that the intervention was implemented before the first dose of DPT/Hepatitis B came due.
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before the first shot
before the first radiation
before the first administration
before the first exposure
before the first obstacle
before the first match
before the first world
before the first performance
before the first control
before the first anthrax
before the traditional dose
before the first rehearsal
before the first visit
before the first page
before the first ad
before the first deal
before the first book
before the first race
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