Sentence examples for before the first application from inspiring English sources

Therefore, the early assessment of toxicity before the first application to man (clinical phase 1) plays a pivotal role in this process.

The randomization was performed in two separate groups for GTs 1/4 and for GTs 2/3. 2 male patients, both randomized into group A, withdrew their consent before the first application of study medication.

Before the first application, the lesions were cleaned with soap and water, debrided, and then dried.

Transthoracic echocardiography was performed before the first application of PEG-Dox and at every 4th cycle of the maintenance chemotherapy.

RNA was extracted from peripheral blood mononuclear cells of 19 rheumatoid arthritis patients before the first application of the TNFα blocker etanercept as well as after 72 hours.

Blood samples were taken before the first application of chemotherapy (day 1) and then daily in the morning during the whole cycle.

Although models to incorporate covariates in network meta-analysis have been presented before, this is the first application where treatment effects act on two separate parameters [ 10- 14].

Immunoglobulin isotypes IgG, IgM and IgA against MCV were measured before and 24 weeks after the first application of RTX in an expanded cohort of 50 patients.

If the heartbeat message is delayed and arrives after the shorter detection time but before the larger detection time, only the first application is informed that a false suspicion occurred.

In intermittent therapy the trough levels are to be obtained before the fourth application of vancomycin with a target level of 10 to 20 mg/l.

Just before the second application (after 72 h), the blood concentration dropped to 49% (5203) and 67% (5204), respectively.> After the second application, the blood values rose at one hour in both animals and the highest concentration was measured again after 18 hours in both animals.