Sentence examples for before the expected onset from inspiring English sources
The questions to be tested were: can treatment before the expected onset prevent the cognitive decline?
We found that H. bilis infection induced diarrhea, weight loss, and IBD in mdr1a−/− mice within 6 to 17 weeks post-inoculation and before the expected onset of spontaneous IBD.
Writing in the New England Journal of Medicine, they say signs appeared up to 25 years before the expected onset of the disease.
In published reports, prophylactic treatment with frovatriptan, started 2 days before the expected onset of headache and continued for 6 days, was always superior to placebo in reducing the frequency of menstrual migraine.
For preventive therapy of EWH the majority of medications have been tested to be started two days before the expected onset of menstrual flow and to be continued for 6 days [10, 22 24].
One day before the expected onset of arthritis, 29 mice got either a high or low dose of Gleevec (comparable to the doses cancer patients take) and 15 got a placebo.
In every case, this training protocol resulted in a typical Purkinje cell CR, that is a strong suppression of simple spike firing that reaches a maximum just before the expected US onset and ending shortly after the US, even though the CS continued for an additional 150 or 600 ms (Fig. 2A).
In 2012, the first DIAN report confirmed that changes begin in the brain about 25 years before expected symptom onset with the decline in A β42 concentrations in the CSF in mutation carriers, as compared with noncarriers [ 47].
ISI, interstimulus interval (between onset of the first CS pulse and the expected US).
Increases in levels of tau in the CSF and in brain atrophy were detected approximately 15 years before expected symptom onset, followed by cerebral hypometabolism and impaired episodic memory approximately 10 years before expected symptom onset and global cognitive impairment starting at 5 years before expected symptom onset.
