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More likely, Sdc is required for dorsal branch cell migration before cell intercalation and linear alignment, and before specification, which is known to occur after the cells leave the dorsal trunk (Ghabrial & Krasnow, 2006).
In the L2 stage, hlh-2prox drives expression of GFP in all four cells; initially, before specification, the level of expression is similar in the unspecified α and β cells but later becomes relatively greater in the AC and αVU than in the βVUs (Sallee and Greenwald 2015).
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The fist occurred in all cereals before the specification of rice, sorghum and maize, whereas the second take place specifically in the lineage leading to maize [ 42].
This temporal separation of these two events allows one to manipulate Wnt/β-catenin signaling in a specific developmental time-window, such as after the A P patterning but before liver specification, thereby leading to the identification of the role of Wnt/β-catenin signaling in liver specification.
"It is unusual to have a third party forum to begin testing products before the specification is formally completed, said Farpoint Group's Mathias.
We found that the expression of hhex and prox1, the earliest liver markers in zebrafish, was severely reduced in the liver region when Bmp or Fgf signaling was blocked just before hepatic specification.
Such protrusion retraction cycles have been documented in multiple neuronal systems, such as by example with stage 2 immature neurites in the classic E18 embryonal hippocampal neurons culture system, just before axonal specification [36].
Taken together, these results show that BMP4 interfered with skeletal myogenesis at a time point after mesoderm induction but before the specification of skeletal muscle.
MAC1 is a small, secreted protein initially expressed throughout the lobes and in part of the connective tissue before AR specification.
Once a naïve T cell is primed by signals received from an antigen-presenting cell, proliferation occurs before lineage specification begins.
Here, we report an alternate method of generating epicardium, epicardium-derived smooth muscle cells (EPI-SMCs) and epicardium-derived cardiac fibroblasts (EPI-CFs) from HPSCs under chemically defined conditions by first inducing an early mesoderm lineage, then LM before further specification to epicardium.
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