Sentence examples for before significant changes in from inspiring English sources

Slope-channel (dis connectivity controls the existence of thresholds or tipping points that need to be crossed before significant changes in downstream sediment dynamics are recorded following human impact.

Next, we estimate the distribution of energy densities at den entry for females in western Hudson Bay during the early 1990s (that is, for a period before significant changes in sea ice break-up occurred7,11), and we use this distribution to estimate their offspring production.

The short induction time was utilized to ensure that the assessment of DKK1 transgene expression was performed before significant changes in TEC subsets or thymic epithelial organization were apparent.

Additionally, data collection occurred in 2011, before significant changes in the Rwanda CHW system were implemented.

It usually takes at least one year before significant changes in joint damage can be observed.

In a paediatric population with septic shock, early myocardial dysfunction was identified with strain echocardiography [ 10], and in a recent experimental study in porcine septic shock, strain echocardiography revealed myocardial dysfunction before significant changes in LVEF were seen [ 11].

Data were normalised and filtered as before and significant changes in gene expression discovered by performing a two-class SAM, using a false discovery rate (FDR) cut-off of 0.1.

Still, even the limited progress is an improvement over stagnant conditions before Hurricane Katrina struck in 2005, officials said — and before the significant changes in governance and instruction that the battered school district here has undergone.

In a meeting at the White House with senior lawmakers, Mr. Bush said that before proposing significant changes in military spending, he would order Donald H. Rumsfeld, the secretary of defense, to oversee a broad review of the nation's military strategy and its armed forces, the aides said.

While housing advocates saw the Thompson case as a way to move beyond Baltimore's segregated history, some are saying the struggles of this pilot program are proof there's still a long way to go before anything significant changes in the city or the country.

It may require longer exposure of treatment before clinically significant changes in patient well-being can be observed; owing to the natural history of advanced pancreatic cancer, as well as the design of the clinical trial, the time of exposure to huachansu was relatively short.