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Figure 1 shows the incidence of breast cancer in England and Wales in 1985 and 1995, plus a third line representing the expected incidence in 1995 based on incidence trends in 1980 86, before screening was started.
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Control subjects, with a history of colorectal cancer before the screening programme was started in 1986 or 1987, were excluded.
A screening examination was started in 1991 ("Screen", n = 13004 a.
But, since the declining trends started before screening was introduced and occurred also in non-screened age groups, improved cancer treatments such as adjuvant chemotherapy and tamoxifen may have been important determinants of breast cancer mortality reduction [ 21].
This decline started before screening was introduced, which does not suggest a screening effect.
Other intestinal parasites were often diagnosed and consequently managed before specific screening for fascioliasis was started.
The study area had not had colorectal cancer screening prior to 1986, and a complete listing of residents had been conducted just before the programme was started.
The current study was started before this recommendation, against a background of widespread use of DDS without G6PD screening.
The review was started before that.
11 12 In addition, our findings support early screening and detection of chronic HCV so that therapy can be started before progression to cirrhosis.
An informed consent and medical screening was completed before starting the study protocol.
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CEO of Professional Science Editing for Scientists @ prosciediting.com