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Future studies are needed to confirm this association, before routine genotyping of SPP1 is considered as part of standard of care in DMD.
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The method is validated by sequencing analysis, and this novel method can be adapted for routine genotyping of SCID model.
Routine genotyping of mice was performed by PCR on DNA isolated from tail biopsies.
Until now, no such problem was observed during routine genotyping of more than 600 Belgian sheep.
Continued improvements in methods and reduced cost of SNP genotyping should ultimately facilitate routine genotyping of mouse strains used in research studies.
The availability of all these SNP and recent innovations in high-throughput SNP-chip genotyping technology have made the routine genotyping of huge SNP panels feasible.
However, genomic selection requires the routine genotyping of large number of young selection candidates, which can be expensive.
Routine genotyping of CSGalNAcT1+/− animals was conducted by PCR using the primers 5′-CCAGCTCCAGGGATCTAACA-3′ and 5′-TGGTTTCCTCTAGCCATTGC-3′.
The generation and routine genotyping of Irs2-deficient mice have been described previously (Withers et al 1998).
Dr. Vargo posed the question, is the clinical benefit of routine genotyping enough to outweigh the cost?
Routine genotyping before clinical medication with oral contraceptives, oestrogens or selective oestrogen receptor modifiers.
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