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Study design should be carefully considered before implications for human health are ascribed to prenatal exposure to stress or antidepressant medication.
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21 22 To help address this, the example used here investigates the effect the pre-test probability has on the performance of junior doctors in interpreting plain x-rays in an emergency department (ED) setting, before considering the implications for similar diagnostic tests.
Even before the implications of this provision became clear, Mr. Boehner strenuously opposed the law, on the ground that it was driving up costs for consumers and employers, and he has led efforts to repeal it.
It said: "It will be some time before the implications of the tighter liquidity and credit conditions now set to prevail well into 2009 become clear, but it is logical that these will not be without consequence for SIG's markets and customers".
Confirmation of these data by other studies is required before resultant implications are considered.
Still, it would be several weeks before the implications of the market crash became clear.
Although we believe that the physiologic principles elucidated here are qualitatively valid, observations made in this animal model clearly would need to be extended into studies of the relevant clinical state before the implications are accepted for medical use.
Finally, we consider evidence on associations between symptomatic presentations and intervals to diagnosis before discussing implications for the design, implementation, and evaluation of public health or health system interventions to achieve the earlier detection of cancer.
Two important issues must be addressed before the implications of this animal model can be fully appreciated.
Before discussing implications of the findings, it is important to consider the study's limitations.
Additional data defining regional health status and the respective medical needs are therefore required before such implications can be made.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com