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Cosmic ray correction and background subtraction were performed on the two-dimensional image before further data processing.
We replaced personal identification numbers used to identify included patients in all healthcare contacts with study identification numbers before further data processing.
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The sequence cleaning step is an essential first step of the sequence processing pipeline before any further data processing in order to allow accurate downstream analysis.
However, the HGDP dataset was generated by Human-550 chips of Illumina and required further data processing before use.
The arithmetic mean was used for further data processing.
The sequences minimized possible analytical artifacts during further data processing.
Further data processing, analysis and visualization were performed using the Resolver software© (version 6.0, Rosetta Inpharmatics).
In further data processing, normalized spot intensity ratios (M') were analyzed.
Further data processing was done with the Perseus 1.5 software.
Sequence data of lengths shorter than 50 bases were not included in further data processing.
Therefore, expensive data acquisition or any further data processing is not required to interpret the signal.
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