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The per-protocol population comprises of patients for whom all of the following apply: has met the in- and exclusion criteria; has taken at least 75% of the study drugs as recorded by MEMS; has not taken any other antimicrobial drug for more than 5 days during the study period; has not taken any prohibited concomitant medication; has not been unblinded before end of study.
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After 12 weeks, subjects were advised to maintain their weight for 2 weeks before end-of-study testing.
Patients are also advised to take the study medication before the end-of-study visit.
Follow-up time ended on 31 December 2010 or earlier if a patient had died before end of the study.
Residents who are pregnant, participants of other clinical trials or plan to leave the area before end of the study period will be excluded.
A subject was censored if he or she died, developed non-pancreatic cancer, or else did not develop pancreatic cancer before end of the study.
LTFU was defined as no patient contact for more than 6 months before the end of study period.
Patients who were censored before the end of study did not differ at baseline from those attending the long-term follow-up.
For proteinuria data, a last-observation-carried-forward approach was used for the mice that died before the end of study.
The numbers of rabbits that died before the end of study were 0, 1, 2 and 10 in the control, 75, 175 and 350 mg/kg/day glyphosate treatment groups, respectively.
4. When analysis cost per life year gained, both an undiscounted estimate and a discount rate of 3% in estimiting future benefits gained were presented [ 16]. 5. Juvenile justice offenders included in this study did not emigrate out of Western Australia before the end of study period.
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