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After 24 h, the glucose level remained lower than that before dosing of the targeting NPs, which was similar with previous report and might be due to a hypoglycemic agent15.
2.2.1 was used in the jar test as described below: the pH of PW was adjusted to desired pH using 0.1 M H2SO4 and 0.1 M NaOH just before dosing of the MSC.
Of all adverse events, 685 (2.8%) occurred before dosing of the study drug, with 475 (69.3%) mild and five (0.7%) severe (table 4).
Tumour response was assessed according to RECIST version 1.0, before dosing of cycle 3, and approximately every 9 weeks thereafter, until withdrawal from the study.
One radiologist (with 8 years experience) who was blinded to treatment groups performed contrast-enhanced US for all groups on days 0, 3 and 7 before dosing of cisplatin.
The mice received training on rotarod for 10 min each day for 3 days before being tested on the first day of 11 week of age before dosing of AMD3100 started (Day 1).
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This augmentation was observed when more than 1.8 microg of Fungizone was injected intravenously before intravenous dosing of FK23.
Video-EEG recordings of baseline activity in the freely moving rats began at least 10 min before oral dosing of RDX.
Plasma samples were obtained on cycle 1 day 1 before dosing from 110 of these patients.
Three additional patients in Group B died before receiving any dose of eltrombopag or placebo.
Blood samples for pharmacokinetic analysis were taken 5 min after the end of the first infusion, 5 min before the second and the third dose and 5 min before the dose of the day after.
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