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We compared a period before CONSORT (1990 1994) with a post-CONSORT period (2004 2008).
It is noteworthy that these authors compared a time period before CONSORT publication with a period thereafter; this approach was also chosen in our report.
However, our results showed that abstract reporting improved significantly before CONSORT; on the other hand, recent reviews [47], [48] of abstract reporting in top impact-factor journals showed improvement also after CONSORT and also that many top journals had not been referring to CONSORT or alternative abstract guidelines, or had referred to old CONSORT versions.
We compared manuscripts published before CONSORT (2000-4) withoseose published after CONSORT (2005-8).
In particular, assuming the most conservative estimate of adherence of 50% before CONSORT, improvements to 60%and70%0% adherence after CONSORT (2005-6 and 2007-8, respectively) would have been required to allow 80% probability of detecting a significant trend.
In the post-CONSORT years, 1997 2003, the term appeared in 85% of the titles or abstracts, compared to 68% in the seven years before CONSORT (1990 96); mean difference was 17%95%5% CI 8.3 to 25.9%; p = 0.001).
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Table 3 shows the percentage of trials that met each of the reporting criteria before and after CONSORT, together with the tests for trend and confidence intervals for absolute change in adherence.
That was just before he consorted with a known gambler with connections to organized crime in his unconscionable effort to defame Dave Winfield.
When considering the change from before to after CONSORT, the general medical journals showed significant improvement in only one criterion: reporting of number of clusters lost to follow-up (absolute improvement 17%, 3%to3131%).
To quantify the magnitude of change in adherence over time, we calculated the absolute change in the proportion of trials meeting each recommendation from before to after CONSORT, together with 95% asymptotic confidence intervals (or exact confidence intervals in the case of small expected frequencies).
Before the publication of the revised CONSORT statement in 2001, the CONSORT Group decided to develop extensions to the main CONSORT statement relevant to specific trial designs.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com