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Mean COMFORT score value was 15.02 before clonidine was started and 13.69 after beginning of clonidine infusion.
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Propofol was started at 50 to 100 μg/kg/min, and after endotracheal intubation, clonidine infusion was started (6 to 20 μg/h).
Infusions were terminated at 28°C before rewarming was started.
Informed consent was obtained before the survey was started.
In the remifentanil-clonidine group, anesthesia was started with remifentanil (0.15 to 0.3 μg/kg/min), followed by etomidate (0.2 to 0.3 mg/kg).
The review was started before that.
Treatment was started before a diagnosis was made.
Before experiments were started, the optimal muscle length was ascertained.
Waiting time before phototherapy could be started was sometimes considerable.
In the latter experiments clonidine was added one hour before LPS administration.
We observed a significant lower consumption of morphine and midazolam after clonidine was introduced.
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