Sentence examples for before altered from inspiring English sources

Nevertheless, further work with larger and independent populations of patients will be needed before altered CaM content can be considered a suitable biomarker for AD diagnosis.

The age distribution of cancer, and particularly of lung cancer in smokers and non-smokers, led to multi-stage models of carcinogenesis long before altered genes were observed in human cancer (Armitage and Doll, 1954; Doll, 1978).

The effects of leptin on GluR1 trafficking involve an increase in PtdIns 3,4,5 P3 levels secondary to PTEN inhibition as the effects of leptin on surface GluR1 staining were associated with increased PtdIns 3,4,5 P3 levels and elevation in PtdIns 3,4,5 P3 levels occurred before altered GluR1 trafficking.

For those two –– frequent –– cancers, it seems therefore that prudence should prevail before altering classical irradiation schedules which have proven their efficacy, while staying open to new concepts and proposing well-designed randomised trials in specific cases.

And he reiterated that he and his colleagues would want to see "substantial improvement" in the labor market before altering course, even in a modest way.

That resulted in an awkward dance by Francoeur, who seemed about to collide with Rodriguez before altering his route to try to avoid the tag.

Property owners must go through a lengthy legal process before altering such a site, often requiring that they obtain permission from relatives.

The officers all made draft statements at High Wycombe police station before altering them and submitting different signed versions to the police watchdog.

If the proposal passes, landlords would have to apply for special permits from the city before altering the facades for the roughly 73 buildings in the district.

But others familiar with the thinking of city officials said Los Angeles would seek an injunction based on the fact that the administration did not allow for the minimum 30-day comment period before altering a federal regulation.

Just as Jesse Owens and Jackie Robinson pursued their athletic dreams and developed superlative skills before altering history, Basil D'Oliveira, who was classified as colored under South African apartheid, wanted only to play at the highest levels of his sport, cricket.