Sentence examples for been very substantially from inspiring English sources

"By investing new equity, Four Seasons' debt has been very substantially reduced and Terra Firma has brought stability to the company," Mr. Hands said in a statement.

Pressed about his being "a victim or potential victim" of hacking he refused to "go into detail about what seems to be a case that has been very substantially investigated by all sorts of bodies.

Nonetheless, the human Ire1α crystals grown from protein that has been very substantially dephosphorylated by λ-phosphatase (see Materials and methods) clearly contain Mg2+-ADP at full occupancy.

The ethnic cleansing of Srebrenica, in other words, was very substantially a success: those Muslim residents not killed were scattered across the earth.

"It means that long rates can remain low without causing the economy to overheat, and therefore the urgency of tightening is very substantially diminished," said Andrew Levin, a Dartmouth College economist.

The coefficients of the indicators for categories of Educational Attainment are all large, negative, and strongly significant.31 In particular, the coefficients for the lowest level of Educational Attainment correspond to odds that are very substantially lower than those of the reference category.

It's very substantially lower than that and we have been in ongoing dialogue with Brian Kennedy on behalf of the Blue Knights during the course of today and we understand that he may be revising his bid during the course of today; certainly over the next 24 hours.

"AB InBev is very substantially undervaluing SABMiller," said SABMiller chairman Jan du Plessis.

In vitro, TRIM5αrh8KR was very substantially impaired in auto-ubiquitination with Ube2W (Fig 7A, compare lanes 2 and 10, and 4 and 12).

Intriguingly, this effect was only observed in a sub-population of replicons, such that the second and third classes were very substantially affected by RITA treatment, whereas the seventh/eight/ninth classes were less affected.

Diet is also an important modifier of clinical penetrance in phenylketonuria, as mentioned in the " Introduction" to this review, where the penetrance of the condition can be very substantially reduced by restricting dietary phenylalanine (van Spronsen 2010).