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Examining mtDNA mutations at the single-cell level has been valuable in understanding cell origin and clonality, the potential mechanism regarding the occurrence and fixation of an mtDNA mutation by random genetic drift or clonal expansion, and the mtDNA mutation process in tumor and post-mitotic cells with age [13] [15], [22], [23], [53].
Such toxicants have been valuable in understanding retinal physiology and degeneration, and in evaluating interventions.
Theoretical work on learning organizations that encompasses the notion of single and double loop learning [ 27, 32] has been valuable in understanding some key components of Lean implementation, although this work may also present challenges, both to the Lean implementation strategy adopted in Saskatchewan or to the program theory we have developed to represent it.
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Knowledge of this is valuable in understanding the early biochemical evolution of the Earth.
Temperature profiles obtained along the central axis were valuable in understanding the different behaviour of the reactor systems.
From a clinical point of view, our results are valuable in understanding the interaction between intensity and energy contributions during high-intensity exercise.
Maps of magnetic thickness and magnetization can be valuable in understanding further the temperature, composition, and structure of Earth's lithosphere.
These results are valuable in understanding the plastic deformation of MGs and may be helpful in designing new MGs with desirable mechanical properties.
Dissecting these pathways should be valuable in understanding the pathogenesis of, and ultimately in designing therapy for, neurodegenerative diseases that feature misfolded proteins.
Comcaac patterns of mobility and cultural meanings of places are valuable in understanding broader movement scenarios that may be applicable to a range of cultures.
These results will be valuable in understanding the evolutionary history of the pvdhfr alleles as well as for designing the malaria control strategies.
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