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96 EuroQol has been validated in stroke populations.
Cognitive status was assessed using the MMSE, which has been validated in stroke [ 15], and administered by experienced personnel trained by the study psychiatrist.
The Hospital Anxiety and Depression Scale has been validated in stroke [ 25 27] but not the acute setting and the Geriatric Depression Scale has not been validated within stroke populations.
The seven HRQOLISP domains have been validated in stroke patients and healthy individuals in whom they demonstrated good face, content, 'known groups' and construct validity as well as internal consistency and test-retest reliability [ 11].
Folstien's MMSE does not perform consistently well in the stroke [ 19 21] and ignores executive functioning, a common deficit in stroke populations; Hodkinson's Abbreviated Mental Test has not been validated in stroke and the properties of Addenbrooke's Cognitive Examination in stroke survivors is sensitive to timing of assessment [ 11, 22].
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93 The scale is validated in stroke populations, and values for "minimal detectable change" and "clinically important difference" 99 are established.
It has also been validated in patients with stroke [ 5, 6].
The psychometric properties of the SS-QOL have been validated in patients with ischemic stroke and intracerebral hemorrhage [ 10, 18, 20].
The diagnosis of stroke has previously been validated in the Danish registry; with a positive predictive value of ischaemic stroke of 97%.
The outcome diagnoses of stroke and pulmonary embolism have previously been validated in the registry; the positive predictive value of ischaemic stroke (I63) was 97%, haemorrhagic strokes only comprised 5.8% of the unspecified strokes (I64), and pulmonary embolism (I26) had a positive predictive value of 82.1%.
The diagnoses of acute myocardial infarction and stroke have been validated in the national patient registry.
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