Sentence examples for been validated in randomized from inspiring English sources
We should emphasize that selection criteria for early versus late tracheostomy have not been validated in randomized controlled trials, although there are certain variables that can help the intensivist in predicting who is likely to need prolonged mechanical ventilation and possibly tracheostomy.
The original five criteria rule has been validated in a randomized clinical trial[ 17].
14 These data have not been validated in a randomized, prospective trial.
Itraconazole therapy has been validated in two randomized controlled trials with reductions of serum IgE levels exceeding 25% when compared with placebo [ 67, 68].
Uniquely for cancer prognostic biomarkers, uPA and PAI-1 have undergone validation in two separate LOE-1 studies; that is, both have been validated in a prospective randomized controlled trial (NCT1317108) and in a pooled analysis of individualized patient characteristics.
The clinical value of AFC-assisted TURBT has been validated in large prospective randomized clinical trials.
In humans, this approach has been validated in a recent randomized study by Lee et al. [ 44].
ABDC inhalation is also used to prevent pulmonary aspergillosis in many lung transplant units but the safety and efficacy of this approach has never been validated in a large randomized placebo-controlled trial.
The Seattle Heart Failure Model (SHFM) is a multifactor risk assessment score for patients with heart failure, which has been validated in several cohorts derived both from randomized controlled trials and from outpatient community practice settings in the USA and Europe.
Selection criteria have not been validated in prospective trials, but virtually all of the randomized controlled trials have used similar criteria.
Also and despite the fact that our assay has been validated in multiple cohorts and data analyses [ 10, 11, 14, 15, 17], neither survival advantage, nor improvement in quality of life has been demonstrated in a prospective randomized trial.
