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In addition this test has been validated in detecting antibodies in harbor seals with brucellosis.
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This analytical approach allows for pharmacologically relevant concentrations of the analytes and their principle metabolites to be detected, and has been validated in close agreement with the US Food and Drug Administration's guidelines for the validation of methods to be used in support of pharmacokinetic studies.
The current protocol of the register, which has been validated in a test-retest situation, can reliably detect postoperative improvements between large groups of patients such as in a registry (Zanoli et al. 2006, Strömqvist et al. 2009b).
The current protocol of the register, which has been validated in a test-retest situation, can reliably detect postoperative improvements between large groups of patients such as those in a registry [ 23, 24].
CRBN65 was validated in an IHC assay for detecting cereblon in FFPE tissues.
Sequences were validated if detected at least twice in two independent PCR reactions.
Probe sets potentially detecting NAT were validated in silico, and microarray results showing expression of NATs were confirmed by strand-specific RT-PCR.
Finally, the detected associations were validated in the METSIM study, providing 3798 non-diabetic and 659 diabetic (type 2) individuals.
The remaining putative novel miRNAs were validated in the following manner: they should be detected in at least two independent experiments, the reads should match perfectly expected mature products from both arms (5p and 3p) and the reads should support that there were a consistent processing of the 5′-end of the mature sequences.
The initiative was announced yesterday in Lausanne, Switzerland, as the International Olympic Committee cleared the way for blood tests to be introduced in Sydney if a reliable method for detecting the banned hormone EPO is validated in time.
The benefit of large samples in improving statistical power and detecting interactions of much smaller effect sizes may be validated in the future.
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