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The novel multi-sensor platform has been validated in controlled buffers and with artificial urine (AU).
Indeed, this approach has been validated in controlled phase III trials in patients with advanced solid tumours (Sandler et al, 2006; Reck et al, 2009).
We and others have identified many non-canonical targets for bacterial DNA-binding proteins that have been validated in controlled experiments.
We acknowledge that indices of FFA insulin sensitivity used in this study have never been validated in controlled studies using an insulin clamp experiment with FFA tracers to measure the sensibility of lipolysis suppression by insulin in euglycemic conditions as well as in conditions of high circulating levels of triglyceride-rich lipoproteins.
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The activity of all enzymes was validated in control samples (not shown).
Uniquely for cancer prognostic biomarkers, uPA and PAI-1 have undergone validation in two separate LOE-1 studies; that is, both have been validated in a prospective randomized controlled trial (NCT1317108) and in a pooled analysis of individualized patient characteristics.
It has been validated in both case-control studies of normal subjects and several patient populations with different types of sleep disorders., In addition, the ESS has been utilized for the assessment of daytime sleepiness in patients with schizophrenia., Scores higher than 10 are considered to indicate significant, i.e., markedly high, daytime sleepiness.
The long-standing combination of radiotherapy, 5-Fluorouracil (5-FU) and Mitomycin-C (MMC) has been validated in a series of large prospective randomised controlled trials [ 9- 13].
The effectiveness of the proposed control system has been validated in various simulations.
The control law has been validated in a probing task involving a compliant robot base and a compliant environment to show the obtained performance.
TiC has been validated in two case control studies in populations known as S. PAU and MARTHA [ 8].
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com