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GEE regression with robust variance estimation has been validated for sample sizes less than 10 [ 30].

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This method for the measurement of MMPs has been validated for other sample types, particularly for tears [ 20].

Because this version of the MOAS has not been validated for this sample, we ask both the patient and the therapist to fill in the questionnaire separately in order to calculate consistency between self-ratings and therapist-ratings.

To validate the results of the commercial direct sandwich ELISA, which has previously only been validated for serum samples, Western Blot assays were performed on oral fluid samples from one animal (V3), collected at 14 days post vaccination.

The method has been validated for food samples according to NORDVAL [ 13] and AFNOR criteria [ 14].

Commercial products are available for the depletion of albumin and immunoglobulins (Igs), although most of these kits have not been validated for dog samples.

Future research should assess of retest reliability of the scale and it would also be useful to assess concurrent validity of the very brief scale against more lengthy measures of functional impairment such as the Social Adjustment Scale [ 30] and the Medical Outcome Study SF-36 [ 31]; however, these scales have not been validated for pathological gambling samples.

After optimization of MS detection parameters, this method has been validated for spiked drinking water samples.

The short form has been validated for use in community samples with children as young as 7 years of age [ 65, 66].

Research into health related quality of life (HRQoL) in schizophrenia has predominantly been conducted using lengthy interviewer administered questionnaires, many of which have not been validated for use with schizophrenic samples.

The MMP-9 TIMP-1 coMMP-9 TIMP-1antified in preoperatively obtained plasma samples from 465 patients with primary breast complexusing a classical commercially available sandwash ELISA, which had not been validated for use with plasma samples by the supplier, and using the recently developed in-solution Proximity Ligation Assay (PLA, Figure  1).

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